Article
Expression and prognostic impact of lncRNAs in acute myeloid leukemia.
Proceedings of the National Academy of Sciences of the United States of America - 30 Dec 2014
Garzon Ramiro, Volinia Stefano, Papaioannou Dimitrios, Nicolet Deedra, Kohlschmidt Jessica, Yan Pearlly S, Mrózek Krzysztof, Bucci Donna, Carroll Andrew J, Baer Maria R, Wetzler Meir, Carter Thomas H, Powell Bayard L, Kolitz Jonathan E, Moore Joseph O, Eisfeld Ann-Kathrin, Blachly James S, Blum William, Caligiuri Michael A, Stone Richard M, Marcucci Guido, Croce Carlo M, Byrd John C, Bloomfield Clara D
Abstract excerpt
Long noncoding RNAs (lncRNAs) are transcripts longer than 200 nucleotides, located within the intergenic stretches or overlapping antisense transcripts of protein coding genes. LncRNAs are involved in numerous biological roles including imprinting, epigenetic regulation, apoptosis, and cell cycle. To determine whether lncRNAs are associated with clinical features and recurrent mutations in older patients (aged...
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