Article
Association between the Trp64Arg polymorphism of the ADRB3 gene and overactive bladder.
Neurourology and urodynamics - 1 Sept 2021
Çırakoğlu Abdullah, Fejzullahu Arta, Benli Erdal, Yuce Ahmet, Ayyıldız Ali, Aynacıoğlu A Şükrü
Abstract excerpt
BACKGROUND: The β3 -adrenergic receptor (ADRB3) is very important in the regulation of the human detrusor muscle function. The well-known tryptophan64arginine polymorphism of the ADRB3 gene alters the response of the receptor to various stimuli, including adrenalin and noradrenalin, and may increase the susceptibility to develop overactive bladder (OAB). Therefore, this study was performed to determine whether...
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