Article
Are β3 -adrenoceptor gene polymorphisms relevant for urology?
Neurourology and urodynamics - 1 Jan 2023
Michel Martin C
Abstract excerpt
AIMS: β3 -adrenoceptors (ARs) are an important drug target for the treatment of overactive bladder syndrome (OAB) and are under investigation for other indications. The human β3 -AR gene is polymorphic; an exchange of amino acid tryptophan (Trp) for arginine (Arg) in position 64 of the receptor protein is the most frequent and best-studied polymorphism. A narrative review on the impact of β3 -AR polymorphisms on...
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