Article
Relation of ADRB3, GEF, ROCK2 gene polymorphisms to clinical findings in overactive bladder.
World journal of urology - 1 Oct 2020
Fırat Elif, Aybek Zafer, Akgün Şakir, Küçüker Kürşat, Akça Hakan, Aybek Hülya
Abstract excerpt
PURPOSE: Adrenergic and cholinergic pathways play an important role in contraction-relaxation harmony in human bladder. Functional changes in any proteins in these pathways may result in overactive bladder. We aimed to investigate whether single gene polymorphisms affecting adrenergic and cholinergic pathways are associated with OAB syndrome. METHODS: 60 patients with idiopathic OAB and 60 healthy controls were...
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