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Are polymorphisms of the β(3)-adrenoceptor gene associated with an altered bladder function?

Neurourology and urodynamics - 1 Mar 2013

Teitsma Christine A, de la Rosette Jean J M C H, Michel Martin C

Abstract excerpt

AIMS: As the presence of a Trp64Arg polymorphism of the gene encoding the β(3)-adrenoceptor (B3AR) has been linked to the presence of overactive bladder, we investigated whether additional polymorphisms are detectable in this gene and explore their relationships parameters related to lower urinary tract function. METHODS: The coding region and adjacent stretches of the B3AR gene was sequenced in 91 patients. In...

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PMID: 22972489
DOI: 10.1002/nau.22305

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