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Article

beta3-Adrenergic receptor Trp64Arg polymorphism and increased body mass index in sleep apnoea.

The European respiratory journal - 1 Oct 2007

Piérola J, Barceló A, de la Peña M, Barbé F, Soriano J B, Sánchez Armengol A, Martínez C, Agustí A

Abstract excerpt

Obesity is an important risk factor for obstructive sleep apnoea syndrome (OSAS), insulin resistance and cardiovascular disease. The substitution of tryptophan 64 with arginine (Trp64Arg) polymorphism (Arg variant) of the beta(3)-adrenergic receptor (ADRB3) has been associated with obesity. In this study, the prevalence of the Trp64Arg ADRB3 polymorphism in a large group of patients with OSAS and its association...

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Source

Identifiers

PMID: 17626108
DOI: 10.1183/09031936.00152006

Genes

ADRB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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beta3-Adrenergic receptor Trp64Arg polymorphism and increased body mass index in sleep apnoea.PMID 17626108Read ↗

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An association between TRP64ARG polymorphism of the B3 adrenoreceptor gene and some metabolic disturbances.Semantic proximity Read ↗

The ADRB3 Trp64Arg variant and BMI: a meta-analysis of 44 833 individuals.Semantic proximity Read ↗

The Trp64Arg polymorphism of the beta3-adrenergic receptor gene is associated with weight changes in obese Japanese men: a 4-year follow-up study.Semantic proximity Read ↗

Meta-analysis of the association of the Trp64Arg polymorphism in the beta3 adrenergic receptor with body mass index.Semantic proximity Read ↗

beta(3) Adrenergic receptor polymorphism and obesity-related phenotypes in hypertensive patients.Semantic proximity Read ↗

[The Trp64Arg polymorphism of beta3-adrenoreceptor gene study in persons with overweight and obesity].Semantic proximity Read ↗

Association of BMI with the beta3-adrenergic receptor gene polymorphism in Japanese: meta-analysis.Semantic proximity Read ↗

The Trp64Arg polymorphism of the beta 3-adrenergic receptor gene is not associated with obesity or type 2 diabetes mellitus in a large population-based Caucasian cohort.Semantic proximity Read ↗

ADRB3 polymorphism rs4994 (Trp64Arg) associates significantly with bodyweight elevation and dyslipidaemias in Saudis but not rs1801253 (Arg389Gly) polymorphism in ARDB1.Semantic proximity Read ↗

beta(3)-adrenergic receptor polymorphism and metabolic syndrome in postmenopausal women.Semantic proximity Read ↗

Trp64Arg polymorphism of the beta 3-adrenergic receptor gene is associated with increased plasma leptin levels in obese Chinese women.Semantic proximity Read ↗

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