Article
The mutation of Trp64Arg in β3-adrenoreceptor-encoding gene is significantly associated with increased hypertension risk and elevated blood pressure: a meta-analysis.
Oncotarget - 11 Jul 2017
Yang Hualing, Cai Dongmiao, Zhu Qingping, Wu Dongjin, Wang Qingxiang, Wang Zhanxiang
Abstract excerpt
This meta-analysis was implemented to test the association of a missense mutation, Trp64Arg, in β3-adrenoreceptor-encoding gene (ADRB3) with both hypertension risk and blood pressure (BP) changes. A systematic search of three publicly-available databases was launched to look for articles published as of December 2016. Qualification appraisal and data extraction were independently done by two researchers. Pooled...
Topics
- Alleles
- Amino Acid Substitution
- Biomarkers
- Blood Pressure
- Female
- Genetic Association Studies
- Genetic Predisposition to Disease
- Genotype
- Humans
- Hypertension
- Male