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Article

The impact of clonal diversity and mosaicism on haematopoietic function in Fanconi anaemia.

British journal of haematology - 1 Jan 2022

Hughes Andrew D, Kurre Peter

Abstract excerpt

Recent advances have facilitated studies of the clonal architecture of the aging haematopoietic system, and provided clues to the mechanisms underlying the origins of hematopoietic malignancy. Much less is known about the clonal composition of haematopoiesis and its impact in bone marrow failure (BMF) disorders, including Fanconi anaemia (FA). Understanding clonality in FA is likely to inform both the marked...

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Identifiers

PMID: 34258754
DOI: 10.1111/bjh.17653

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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