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Article

EGFR and KRAS Mutations in Lung Parenchyma of Subjects With EGFR/KRAS Wild-Type Lung Adenocarcinoma.

Pathology oncology research : POR - 1 Jan 2021

Chalela Roberto, González-García Jose Gregorio, Khilzi Karys, Curull Víctor, Sánchez-Font Albert, Longarón Raquel, Rodrigo-Calvo María Teresa, Martín-Ontiyuelo Clara, Gea Joaquim, Bellosillo Beatríz

Abstract excerpt

The acquisition of driver mutations in non-tumoral cells appears to be very important during the carcinogenesis of adenocarcinoma (ADC). Recent studies suggest that cancer-related mutations may not necessarily be present only in malignant cells, but also in histologically "healthy cells". Objective: to demonstrate the presence of EGFR or KRAS mutations in non-tumoral lung cells in subjects with ADC and negative...

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Identifiers

PMID: 34257550
DOI: 10.3389/pore.2021.598292
PMCID: PMC8262165

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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