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Article

Molecular changes of epidermal growth factor receptor (EGFR) and KRAS and their impact on the clinical outcomes in surgically resected adenocarcinoma of the lung.

Lung cancer (Amsterdam, Netherlands) - 1 Jan 2008

Kim Young Tae, Kim Tae-You, Lee Dong Soon, Park Sun Jung, Park Ju-Yeon, Seo Soon-Jung, Choi Hyo-Seon, Kang Hee Jung, Hahn Seokyung, Kang Chang Hyun, Sung Sook Whan, Kim Joo Hyun

Abstract excerpt

Recent studies have reported that clinical response to epidermal growth factor receptor (EGFR) inhibitors is associated with somatic changes of EGFR in the advanced stage of lung cancer. However, there is no clear data demonstrating whether such molecular changes of EGFR per se can affect the clinical outcome of early stage cancer after surgical resection. DNA mutations of EGFR and KRAS were investigated in 71...

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Identifiers

PMID: 17904685
DOI: 10.1016/j.lungcan.2007.08.008

Genes

EGFR
KRAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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