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Article

A novel transcriptional risk score for risk prediction of complex human diseases.

Genetic epidemiology - 1 Dec 2021

Shan Nayang, Xie Yuhan, Song Shuang, Jiang Wei, Wang Zuoheng, Hou Lin

Abstract excerpt

Recently polygenetic risk score (PRS) has been successfully used in the risk prediction of complex human diseases. Many studies incorporated internal information, such as effect size distribution, or external information, such as linkage disequilibrium, functional annotation, and pleiotropy among multiple diseases, to optimize the performance of PRS. To leverage on multiomics datasets, we developed a novel...

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Identifiers

PMID: 34245595
DOI: 10.1002/gepi.22424
PMCID: PMC8604733

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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