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Characterization of rifampicin-resistant Mycobacterium tuberculosis in Khyber Pakhtunkhwa, Pakistan.

Scientific reports - 9 Jul 2021

Khan Anwar Sheed, Phelan Jody E, Khan Muhammad Tahir, Ali Sajid, Qasim Muhammad, Napier Gary, Campino Susana, Ahmad Sajjad, Cabral-Marques Otavio, Zhang Shulin, Rahman Hazir, Wei Dong-Qing, Clark Taane G, Khan Taj Ali

Abstract excerpt

Tuberculosis (TB), caused by Mycobacterium tuberculosis, is endemic in Pakistan. Resistance to both firstline rifampicin and isoniazid drugs (multidrug-resistant TB; MDR-TB) is hampering disease control. Rifampicin resistance is attributed to rpoB gene mutations, but rpoA and rpoC loci may also be involved. To characterise underlying rifampicin resistance mutations in the TB endemic province of Khyber...

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Identifiers

PMID: 34244539
DOI: 10.1038/s41598-021-93501-4
PMCID: PMC8270973

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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