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Characterization of mutations conferring extensive drug resistance to Mycobacterium tuberculosis isolates in Pakistan.

Antimicrobial agents and chemotherapy - 1 Dec 2011

Ali Asho, Hasan Rumina, Jabeen Kauser, Jabeen Nusrat, Qadeer Ejaz, Hasan Zahra

Abstract excerpt

The increasing incidence of extensively drug-resistant (XDR) Mycobacterium tuberculosis in high-tuberculosis-burden countries further highlights the need for improved rapid diagnostic assays. An increasing incidence of XDR M. tuberculosis strains in Pakistan has been reported, but drug resistance-associated mutations in these strains have not been evaluated previously. We sequenced the "hot-spot" regions of rpoB,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21911575
DOI: 10.1128/AAC.05101-11
PMCID: PMC3232797

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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