Mutation analysis for detection of drug resistance in mycobacterium tuberculosis isolates from Khyber Pakhtunkhwa, Pakistan.

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Article

Mutation analysis for detection of drug resistance in mycobacterium tuberculosis isolates from Khyber Pakhtunkhwa, Pakistan.

JPMA. The Journal of the Pakistan Medical Association - 1 Nov 2017

Ahmad Bashir, Idrees Muhammad, Ahmad Kafeel, Bashir Shumaila, Ahmad Sajjad, Lin-Fang Huang

Abstract excerpt

OBJECTIVE: To examine the frequency and distribution of mutations in the 'hot spot regions' of drug-resistant genes. METHODS: The study was conducted at Provincial Tuberculosis Reference Laboratory, Peshawar, Pakistan, from April 2015 to March 2016, and comprised sputum samples. Isolates were tested for drug susceptibility and resistant isolates were investigated for mutations analysis in the 'hot spot regions'...

Topics

Antitubercular Agents
Cohort Studies
DNA Mutational Analysis
DNA, Bacterial
Drug Resistance, Multiple, Bacterial
Humans
Microbial Sensitivity Tests
Mutation
Mycobacterium tuberculosis
Pakistan
Tuberculosis, Multidrug-Resistant

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Open in PubMed

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PMID: 29171560

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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