Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study.

Frontiers in endocrinology - 1 Jan 2021

Livingstone Katherine M, Tan Mun Hua, Abbott Gavin, Duckham Rachel L, Croft Larry, Ward Joey, McEvoy Mark, Keske Michelle A, Austin Christopher, Bowe Steven J

Abstract excerpt

Body composition (fat, skeletal muscle and bone mass) is an important determinant of overall health and risk of endocrine disorders such as type 2 diabetes and osteoporosis. Although diet and physical activity are strongly implicated, body composition is also heritable. We conducted a discovery genome-wide association study on 31 phenotypes from the three-compartment body composition model (fat, lean and bone...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipose Tissue
Share to Biological Specimen Banks

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Body Composition

Share to Bone Density

Share to Genome-Wide Association Study

Share to Models, Biological

Share to Muscle, Skeletal

Share to United Kingdom

Source

Open in PubMed Open full text

Identifiers

PMID: 34239500
DOI: 10.3389/fendo.2021.692677
PMCID: PMC8259458

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study.PMID 34239500Read ↗

Sex-stratified GWAS of Body Fat Percentage after Adjusting for Testosterone and SHBG in the UK BiobankSemantic proximity Read ↗

Genetic underpinnings of adiposity : from GWAS discovery to functional characterisationSemantic proximity Read ↗

Body composition subphenotypes, cardiometabolic risk and incident outcomes: validation in the population-based NAKO and UK Biobank imaging cohortsSemantic proximity Read ↗

Health Implications Associated with Fat-Free Mass: A Phenome-Wide Mendelian Randomization Study.Semantic proximity Read ↗

Four pleiotropic loci associated with fat mass and lean mass.Semantic proximity Read ↗

Uncovering covariance patterns across energy balance traits enables the discovery of new obesity‐related genesSemantic proximity Read ↗

Deep learning and genome-wide association meta-analyses of bone marrow adiposity in the UK Biobank.Semantic proximity Read ↗

Body fat percentage and hypertension risk: A population-based observational and Mendelian randomization study.Semantic proximity Read ↗

DNA methylation marks associated with body composition in children from India and the Gambia - findings from the EMPHASIS studySemantic proximity Read ↗

Multi-Trait Body Shape Phenotypes and Breast Cancer Risk in Postmenopausal Women: A Causal Mediation Analysis in the UK Biobank Cohort.Semantic proximity Read ↗

Three pleiotropic loci associated with bone mineral density and lean body mass.Semantic proximity Read ↗

Gene-centric meta-analyses of 108 912 individuals confirm known body mass index loci and reveal three novel signals.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.