Article
Multi-Trait Body Shape Phenotypes and Breast Cancer Risk in Postmenopausal Women: A Causal Mediation Analysis in the UK Biobank Cohort.
Journal of epidemiology and global health - 1 Jun 2024
Amadou Amina, Freisling Heinz, Sedlmeier Anja M, Bohmann Patricia, Fontvieille Emma, Weber Andrea, Konzok Julian, Stein Michael J, Peruchet-Noray Laia, Jansana Anna, Noh Hwayoung, His Mathilde, Gan Quan, Baurecht Hansjörg, Fervers Béatrice
Abstract excerpt
Body shape phenotypes combining multiple anthropometric traits have been linked to postmenopausal breast cancer (BC). However, underlying biological pathways remain poorly understood. This study investigated to what extent the associations of body shapes with postmenopausal BC risk is mediated by biochemical markers. The study included 176,686 postmenopausal women from UK Biobank. Four body shape phenotypes were...
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