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Article

Body fat percentage and hypertension risk: A population-based observational and Mendelian randomization study.

Medicine - 10 Apr 2026

Qu Yinuo, Jiang Chunqi, Wang Muning, Chen Yirui, Liu Zhiyuan, Zhang Ziyi, Li Hongyu, Gui Hongxin, Zhang Zixin, Wang Mengyang

Abstract excerpt

This study aimed to investigate the association and potential causal relationship between body fat percentage (BFP) and hypertension, with a focus on sex-specific thresholds and clinical implications for prevention. We integrated data from the National Health and Nutrition Examination Survey (1999-2018; n = 25,957) and summary-level genome-wide association studies (GWAS) from United Kingdom Biobank and Finnish...

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PMID: 41961676
DOI: 10.1097/MD.0000000000048262

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