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Article

Impact of VKORC1, CYP2C9, and CYP4F2 Polymorphisms on Optimal Warfarin Dose: Does Ethnicity Matters?

American journal of therapeutics - 1 Jan 2000

Li Jia X, Kim Moo H, Song Kai, Guo Long Z, Jin En Z, Kim Soo J, Lee Kwang M, Serebruany Victor

Abstract excerpt

BACKGROUND: Conventional anticoagulation with warfarin remains the cornerstone strategy for numerous preventive strategies. It is established that Asian patients require lower warfarin doses than Caucasians potentially attributing to the genetic polymorphism (GP) differences. AREAS OF UNCERTAINTY: The impact of GP on optimal warfarin dose (OWD) in Koreans is unclear when compared with other ethnicities. It is...

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PMID: 34228652
DOI: 10.1097/MJT.0000000000000845

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