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Article

Shared genetic architecture between neuroticism, coronary artery disease and cardiovascular risk factors.

Translational psychiatry - 17 Jun 2021

Torgersen Kristin, Bahrami Shahram, Frei Oleksandr, Shadrin Alexey, Connell Kevin S O', Smeland Olav B, Munkhaugen John, Djurovic Srdjan, Dammen Toril, Andreassen Ole A

Abstract excerpt

Neuroticism is associated with poor health, cardiovascular disease (CVD) risk factors and coronary artery disease (CAD). The conditional/conjunctional false discovery rate method (cond/conjFDR) was applied to genome wide association study (GWAS) summary statistics on neuroticism (n = 432,109), CAD (n = 184,305) and 12 CVD risk factors (n = 188,577-339,224) to investigate genetic overlap between neuroticism and...

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Identifiers

PMID: 34226488
DOI: 10.1038/s41398-021-01466-9
PMCID: PMC8257646

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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