Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association between neuroticism, genetic susceptibility, and peripheral artery disease risk: a prospective study in UK Biobank.

European archives of psychiatry and clinical neuroscience - 1 Feb 2026

Wang Guoying, Rao Qi, Lei Fang, Tian Yu, Mao Li, He Jinxing, Lin Lijin, Huang Chuhua

Abstract excerpt

BACKGROUND: Neuroticism is one of five personality traits characterized by a tendency to generate and intensify negative emotions in the face of stress and is linked to an elevated incidence of cardiovascular disease (CVD). However, the pathogenesis of peripheral artery disease (PAD) differs from other CVDs. This study aimed to investigate the association of neuroticism with PAD and to examine whether genetic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Biological Specimen Banks

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Follow-Up Studies

Share to Genetic Predisposition to Disease

Share to Neuroticism

Share to Peripheral Arterial Disease

Share to UK Biobank

Share to United Kingdom

Source

Identifiers

PMID: 40956418
DOI: 10.1007/s00406-025-02111-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association between neuroticism, genetic susceptibility, and peripheral artery disease risk: a prospective study in UK Biobank.PMID 40956418Read ↗

Genetic variation mediating neuroticism's influence on cardiovascular diseases.Semantic proximity Read ↗

Exploring Causal Association between Neuroticism Subclusters and Risk of Coronary Atherosclerosis: A Mendelian Randomization Analysis based on Genome-Wide Association StudiesSemantic proximity Read ↗

Shared genetic architecture between neuroticism, coronary artery disease and cardiovascular risk factors.Semantic proximity Read ↗

Pleiotropy between neuroticism and physical and mental health: findings from 108 038 men and women in UK BiobankSemantic proximity Read ↗

Depression and neuroticism in patients with peripheral arterial disease: a cross-sectional studySemantic proximity Read ↗

Genetic contribution to two factors of neuroticism is associated with affluence, better health, and longer lifeSemantic proximity Read ↗

Effect of worry, depression, and sensitivity to environmental stress owing to neurotic personality on risk of cardiovascular disease: A Mendelian randomization study.Semantic proximity Read ↗

The relationship between neuroticism and inflammatory markers: a twin study.Semantic proximity Read ↗

Causal influences of neuroticism on mental health and cardiovascular disease.Semantic proximity Read ↗

Neuroticism personality traits are linked to adverse cardiovascular phenotypes in the UK BiobankSemantic proximity Read ↗

Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism.Semantic proximity Read ↗

Causal association between Neuroticism and risk of aortic aneurysm: A bidirectional two-sample Mendelian randomization study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.