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Article

Identifying cross-disease components of genetic risk across hospital data in the UK Biobank.

Nature genetics - 1 Jan 2020

Cortes Adrian, Albers Patrick K, Dendrou Calliope A, Fugger Lars, McVean Gil

Abstract excerpt

Genetic risk factors frequently affect multiple common human diseases, providing insight into shared pathophysiological pathways and opportunities for therapeutic development. However, systematic identification of genetic profiles of disease risk is limited by the availability of both comprehensive clinical data on population-scale cohorts and the lack of suitable statistical methodology that can handle the scale...

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Identifiers

PMID: 31873298
DOI: 10.1038/s41588-019-0550-4
PMCID: PMC6974401

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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