Article
CD32+CD4+ T Cells Sharing B Cell Properties Increase With Simian Immunodeficiency Virus Replication in Lymphoid Tissues.
Frontiers in immunology - 1 Jan 2021
Huot Nicolas, Rascle Philippe, Planchais Cyril, Contreras Vanessa, Passaes Caroline, Le Grand Roger, Beignon Anne-Sophie, Kornobis Etienne, Legendre Rachel, Varet Hugo, Saez-Cirion Asier, Mouquet Hugo, Jacquelin Beatrice, Müller-Trutwin Michaela
Abstract excerpt
CD4 T cell responses constitute an important component of adaptive immunity and are critical regulators of anti-microbial protection. CD4+ T cells expressing CD32a have been identified as a target for HIV. CD32a is an Fcγ receptor known to be expressed on myeloid cells, granulocytes, B cells and NK cells. Little is known about the biology of CD32+CD4+ T cells. Our goal was to understand the dynamics of CD32+CD4+...
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