Article
In depth comparative phenotyping of blood innate myeloid leukocytes from healthy humans and macaques using mass cytometry.
Cytometry. Part A : the journal of the International Society for Analytical Cytology - 1 Oct 2017
Elhmouzi-Younes Jamila, Palgen Jean-Louis, Tchitchek Nicolas, Delandre Simon, Namet Inana, Bodinham Caroline L, Pizzoferro Kathleen, Lewis David J M, Le Grand Roger, Cosma Antonio, Beignon Anne-Sophie
Abstract excerpt
Comparative immune-profiling of innate responses in humans and non-human primates is important to understand the pathogenesis of infectious and chronic inflammatory diseases as well as for the preclinical development of vaccines and immune therapies. However, direct comparisons of the two species are rare and were never performed using mass cytometry. Here, whole-blood-derived leukocytes from healthy humans and...
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