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Preferential Exhaustion and Loss of Predominant Reservoir in Gut-Associated Lymph Nodes of a SIVmac239-Infected Rhesus Macaque with Terminal AIDS

2026-06-12

Abstract excerpt

Gut‑associated lymph nodes (GALNs) constitute an important anatomical reservoir during early and chronic human immunodeficiency virus (HIV)/simian immunodeficiency virus (SIV) infection, but the fate of this compartment during terminal AIDS remains unclear. This study investigated viral persistence and lymph node injury in a rhesus macaque with long‑term SIVmac239 infection and end-stage AIDS, characterized by pro...

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Literature Corpus work
483b8e76-f305-504b-be47-b69fcb5cbb5e
DOI
10.20944/preprints202606.0958.v1
Open publication

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