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Article

Spectrum of Atazanavir-Selected Protease Inhibitor-Resistance Mutations

5 May 2022

Abstract excerpt

Ritonavir-boosted atazanavir is an option for second-line therapy in low- and middle-income countries (LMICs). We analyzed publicly available HIV-1 protease sequences from previously PI-naïve patients with virological failure (VF) following treatment with atazanavir. Overall, 1497 patient sequences were identified, including 740 reported in 27 published studies and 757 from datasets assembled for this analysis. A...

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PMID: 35631067
DOI: 10.3390/pathogens11050546

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