Article
Molecular subversion of Cdc42 signalling in cancer.
Biochemical Society transactions - 30 Jun 2021
Murphy Natasha P, Binti Ahmad Mokhtar Ana Masara, Mott Helen R, Owen Darerca
Abstract excerpt
Cdc42 is a member of the Rho family of small GTPases and a master regulator of the actin cytoskeleton, controlling cell motility, polarity and cell cycle progression. This small G protein and its regulators have been the subject of many years of fruitful investigation and the advent of functional genomics and proteomics has opened up new avenues of exploration including how it functions at specific locations in...
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