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Article

Cdc42 is highly expressed in colorectal adenocarcinoma and downregulates ID4 through an epigenetic mechanism

1 Jul 2008

Abstract excerpt

Cdc42, a member of Rho GTPases family, is involved in the regulation of several cellular functions, such as rearrangement of actin cytoskeleton, membrane trafficking, cell-cycle progression, and transcriptional regulation. Aberrant expression or activity of Cdc42 has been reported in several tumours. Here, the specific role of Cdc42 in development and progression of colorectal cancer was analyzed through...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 18575765
DOI: 10.3892/ijo.33.1.185

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