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Article

RNA-binding protein Maca is crucial for gigantic male fertility factor gene expression, spermatogenesis, and male fertility, in Drosophila.

PLoS genetics - 1 Jun 2021

Zhu Li, Fukunaga Ryuya

Abstract excerpt

During spermatogenesis, the process in which sperm for fertilization are produced from germline cells, gene expression is spatiotemporally highly regulated. In Drosophila, successful expression of extremely large male fertility factor genes on Y-chromosome spanning some megabases due to their gigantic intron sizes is crucial for spermatogenesis. Expression of such extremely large genes must be challenging, but...

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PMID: 34181646
DOI: 10.1371/journal.pgen.1009655
PMCID: PMC8248703

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