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Identification of Novel Biallelic TLE6 Variants in Female Infertility With Preimplantation Embryonic Lethality

11 Jun 2021

Abstract excerpt

Preimplantation embryonic lethality is a rare cause of primary female infertility. It has been reported that variants in the transducin-like enhancer of split 6 (TLE6) gene can lead to preimplantation embryonic lethality. However, the incidence of TLE6 variants in patients with preimplantation embryonic lethality is not fully understood. In this study, we identified four patients carrying novel biallelic TLE6...

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PMID: 34178031
DOI: 10.3389/fgene.2021.666136

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