Article
Impact of lung function on cardiovascular diseases and cardiovascular risk factors: a two sample bidirectional Mendelian randomisation study.
Thorax - 1 Feb 2022
Au Yeung Shiu Lun, Borges Maria Carolina, Lawlor Debbie A, Schooling C Mary
Abstract excerpt
INTRODUCTION: Observational studies suggested lung function is inversely associated with cardiovascular disease (CVD) although these studies could be confounded. We conducted a two sample Mendelian randomisation study using summary statistics from genome-wide association studies (GWAS) to clarify the role of lung function in CVD and its risk factors, and conversely the role of CVD in lung function. METHODS: We...
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