Article
Genetic Correlation and Bidirectional Causal Association Between Type 2 Diabetes and Pulmonary Function.
Frontiers in endocrinology - 1 Jan 2021
Zhu Jiahao, Zhao Huanling, Chen Dingwan, Tse Lap Ah, Kinra Sanjay, Li Yingjun
Abstract excerpt
Background: Observational studies have shown possible bidirectional association between type 2 diabetes (T2D) and pulmonary function, but the causality is not well defined. The purpose of this study is to investigate genetic correlation and causal relationship of T2D and glycemic traits with pulmonary function. Methods: By leveraging summary statistics from large-scale genome-wide association studies, linkage...
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