Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Oncogenic potential of human pluripotent stem cell‐derived lung organoids with HER2 overexpression

21 Jun 2021

Abstract excerpt

Lung adenocarcinoma (LUAD) is the most common types among lung cancers generally arising from terminal airway and understanding of multistep carcinogenesis is crucial to develop novel therapeutic strategy for LUAD. Here we used human induced pluripotent stem cells (hiPSCs) to establish iHER2-hiPSCs in which doxycycline induced the expression of the oncoprotein human epidermal growth factor receptor 2...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Medical Imaging and Pathology Studies
Share to Renal and related cancers
Share to Tumors and Oncological Cases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34152598
DOI: 10.1002/ijc.33713

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Oncogenic potential of human pluripotent stem cell‐derived lung organoids with HER2 overexpressionPMID 34152598Read ↗

Modeling diverse genetic subtypes of lung adenocarcinoma with a next-generation alveolar type 2 organoid platformSemantic proximity Read ↗

Modeling diverse genetic subtypes of lung adenocarcinoma with a next-generation alveolar type 2 organoid platformSemantic proximity Read ↗

Human pluripotent stem cell‐derived lung organoids: Potential applications in development and disease modelingSemantic proximity Read ↗

Alveolar progenitor cells and the origin of lung cancer.Semantic proximity Read ↗

E2F1-autophagy-ALDH1A1 axis enhances self-renewal and drug resistance of lung cancer stem-like cells in a p53-dependent mannerSemantic proximity Read ↗

In vitro generation of human pluripotent stem cell derived lung organoidsSemantic proximity Read ↗

Mesenchymal stromal cells promote the formation of lung cancer organoids via Kindlin-2Semantic proximity Read ↗

Alveolar epithelial type 1 cells serve as a cell of origin for lung adenocarcinoma with distinct molecular and phenotypic presentationSemantic proximity Read ↗

Patient-derived lung cancer organoids as in vitro cancer models for therapeutic screeningSemantic proximity Read ↗

Human pluripotent stem cells for the modelling and treatment of respiratory diseasesSemantic proximity Read ↗

A robust human airway organoid platform enables scalable expansion and trajectory mapping of pulmonary neuroendocrine cellsSemantic proximity Read ↗

An atlas of epithelial cell states and plasticity in lung adenocarcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.