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Article

Identification of New Rare Variants Associated With Familial Autoimmune Thyroid Diseases by Deep Sequencing of Linked Loci.

The Journal of clinical endocrinology and metabolism - 21 Oct 2021

Li Cheuk Wun, Sachidanandam Ravi, Jayaprakash Anitha, Yi Zhengzi, Zhang Weijia, Stefan-Lifshitz Mihaela, Concepcion Erlinda, Tomer Yaron

Abstract excerpt

CONTEXT: Genetic risk factors play a major role in the pathoetiology of autoimmune thyroid diseases (AITD). So far, only common risk variants have been identified in AITD susceptibility genes. Recently, rare genetic variants have emerged as important contributors to complex diseases, and we hypothesized that rare variants play a key role in the genetic susceptibility to AITD. OBJECTIVE: We aimed to identify new...

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Identifiers

PMID: 34143178
DOI: 10.1210/clinem/dgab440
PMCID: PMC8530708

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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