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Article

Recent advances in the association studies of autoimmune thyroid disease and the functional characterization of AITD-related transcription factor ZFAT.

Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology - 1 Jan 2010

Nakabayashi Kazuhiko, Shirasawa Senji

Abstract excerpt

Autoimmune thyroid disease (AITD), including Graves'disease (GD) and Hashimoto's thyroiditis (HT), is caused by immune response to self-thyroid antigens, and affects up to 2-5% of the general population. Twin studies and familial aggregation have clearly indicated the involvement of genetic factors with AITD in addition to environmental factors. Known AITD-susceptibility genes are classified into three...

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Autoantigens
Genetic Loci
Graves Disease
Hashimoto Disease
HLA Antigens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 20453441
DOI: 10.2177/jsci.33.66

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ZFAT

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