Article
GWAS in autoimmune thyroid disease: redefining our understanding of pathogenesis.
Nature reviews. Endocrinology - 1 May 2013
Simmonds Matthew J
Abstract excerpt
The ability of the immune system to protect the body from attack by foreign antigens is essential for human survival. The immune system can, however, start to attack the body's own organs. An autoimmune response against components of the thyroid gland affects 2-5% of the general population. Considerable familial clustering is also observed in autoimmune thyroid disease (AITD). Teasing out the genetic contribution...
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