Article
Rad21l1 cohesin subunit is dispensable for spermatogenesis but not oogenesis in zebrafish.
PLoS genetics - 1 Jun 2021
Blokhina Yana P, Frees Michelle A, Nguyen An, Sharifi Masuda, Chu Daniel B, Bispo Kristi, Olaya Ivan, Draper Bruce W, Burgess Sean M
Abstract excerpt
During meiosis I, ring-shaped cohesin complexes play important roles in aiding the proper segregation of homologous chromosomes. RAD21L is a meiosis-specific vertebrate cohesin that is required for spermatogenesis in mice but is dispensable for oogenesis in young animals. The role of this cohesin in other vertebrate models has not been explored. Here, we tested if the zebrafish homolog Rad21l1 is required for...
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