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Article

Circulating tumor DNA tracking through driver mutations as a liquid biopsy-based biomarker for uveal melanoma.

Journal of experimental & clinical cancer research : CR - 16 Jun 2021

Bustamante Prisca, Tsering Thupten, Coblentz Jacqueline, Mastromonaco Christina, Abdouh Mohamed, Fonseca Cristina, Proença Rita P, Blanchard Nadya, Dugé Claude Laure, Andujar Rafaella Atherino Schmidt, Youhnovska Emma, Burnier Miguel N, Callejo Sonia A, Burnier Julia V

Abstract excerpt

BACKGROUND: Uveal melanoma (UM) is the most common intraocular tumor in adults. Despite good primary tumor control, up to 50% of patients develop metastasis, which is lethal. UM often presents asymptomatically and is usually diagnosed by clinical examination and imaging, making it one of the few cancer types diagnosed without a biopsy. Hence, alternative diagnostic tools are needed. Circulating tumor DNA (ctDNA)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34134723
DOI: 10.1186/s13046-021-01984-w
PMCID: PMC8207750

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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