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Article

Evaluating Circulating Tumor DNA From the Cerebrospinal Fluid of Patients With Melanoma and Leptomeningeal Disease.

Journal of neuropathology and experimental neurology - 1 Jul 2018

Ballester Leomar Y, Glitza Oliva Isabella C, Douse Dzifa Y, Chen Melissa M, Lan Chieh, Haydu Lauren E, Huse Jason T, Roy-Chowdhuri Sinchita, Luthra Rajyalakshmi, Wistuba Ignacio I, Davies Michael A

Abstract excerpt

Circulating tumor DNA (ctDNA) refers to tumor-derived cell-free DNA that circulates in body fluids. Fluid samples are easier to collect than tumor tissue, and are amenable to serial collection at multiple time points during the course of a patient's illness. Studies have demonstrated the feasibility of performing mutation profiling from blood samples in cancer patients. However, detection of ctDNA in the blood of...

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Identifiers

PMID: 29873738
DOI: 10.1093/jnen/nly046
PMCID: PMC6005029

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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