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Article

Convergent and distributed effects of the 3q29 deletion on the human neural transcriptome.

Translational psychiatry - 15 Jun 2021

Sefik Esra, Purcell Ryan H, Walker Elaine F, Bassell Gary J, Mulle Jennifer G

Abstract excerpt

The 3q29 deletion (3q29Del) confers high risk for schizophrenia and other neurodevelopmental and psychiatric disorders. However, no single gene in this interval is definitively associated with disease, prompting the hypothesis that neuropsychiatric sequelae emerge upon loss of multiple functionally-connected genes. 3q29 genes are unevenly annotated and the impact of 3q29Del on the human neural transcriptome is...

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Identifiers

PMID: 34131099
DOI: 10.1038/s41398-021-01435-2
PMCID: PMC8206125

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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