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Article

Hand in hand: intrinsic and extrinsic drivers of aging and clonal hematopoiesis.

Experimental hematology - 1 Nov 2020

SanMiguel Jennifer M, Young Kira, Trowbridge Jennifer J

Abstract excerpt

Over the past 25 years, the importance of hematopoietic stem cell (HSC) aging in overall hematopoietic and immune system health span has been appreciated. Much work has been done in model organisms to understand the intrinsic dysregulation that occurs in HSCs during aging, with the goal of identifying modifiable mechanisms that represent the proverbial "fountain of youth." Much more recently, the discovery of...

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Identifiers

PMID: 32991978
DOI: 10.1016/j.exphem.2020.09.197
PMCID: PMC7736302

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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