Article
Selection of Cord Blood Unit by CD34+ Cell and GM-CFU Numbers and Allele-Level HLA Matching in Single Cord Blood Transplantation.
Transplantation and cellular therapy - 1 Oct 2023
Morishima Yasuo, Watanabe-Okochi Naoko, Kai Syunro, Azuma Fumihiro, Kimura Takafumi, Matsumoto Kayoko, Hatasa Shizuyo, Araki Nobuo, Miyamoto Akira, Sekimoto Tatsuya, Minemoto Mutsuko, Ishii Hiroyuki, Uchida Naoyuki, Takahashi Satoshi, Tanaka Masatsugu, Shingai Naoki, Miyakoshi Shigesaburo, Kozai Yasuji, Onizuka Makoto, Eto Tetsuya, Ishimaru Fumihiko, Kanda Junya, Ichinohe Tatsuo, Atsuta Yoshiko, Takanashi Minoko, Kato Koji
Abstract excerpt
In Japan, only single-unit cord blood transplantations (CBTs) are typically performed, and their number has increased over the last 23 years, with ongoing improvement in results. In most cases, CBTs with multiple HLA mismatches are used, owing to a low HLA barrier, and lower engraftment rate is a problem that must be overcome. Here, as part of an effort to improve guidelines for the selection and processing of CB...
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