Article
Relationship between polymorphisms in the FAS/FASL death receptor system and progression of low-grade precursor lesions infected with high-risk human papilloma virus.
Human immunology - 1 Sept 2021
Santaclara Vicente, Torres-Moreno Daniel, Bernal-Mañas Carmen M, Isaac María Alejandra, Ortiz-Reina Sebastián, Conesa-Zamora Pablo
Abstract excerpt
Squamous intraepithelial lesions (SIL) and cervical cancer are primary due to suboptimal immune response against human papillomavirus (HPV). The FASL/FAS system is a trigger of extrinsic pathway apoptosis. The distribution of polymorphisms rs1800682 (-670 A > G) FAS and rs763110 (-844C > T) FASL was studied in cervical smears from 372 females (182 with stable or regressed low-grade SIL (LSIL) (groupI) and a group...
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