Article
Fas/CD95 promoter polymorphism gene and its relationship with cervical carcinoma.
European journal of gynaecological oncology - 1 Jan 2009
Zucchi F, da Silva I D C G, Ribalta J C L, de Souza N C N, Speck N M de Góis, Girão M J B C, Brenna S M F, Syrjänen K J
Abstract excerpt
OBJECTIVE: Apoptosis is an important fail-safe control in human papillomavirus (HPV)-associated carcinogenesis. We tested the hypothesis that the A/G polymorphism at -670 of Fas promoter is associated with an increased risk for cervical cancer, using a matched case-control setting. METHODS: The material in this case-control study consisted of 91 patients with cervical carcinoma and 176 population-based control...
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