Article
Fas gene promoter -670 polymorphism (A/G) is associated with cervical carcinogenesis.
Gynecologic oncology - 1 Jul 2005
Ueda Masatsugu, Hung Yao-Ching, Terai Yoshito, Yamaguchi Hiroyuki, Saito Junko, Nunobiki Osamu, Noda Sadamu, Ueki Minoru
Abstract excerpt
OBJECTIVE: To investigate the biological significance of single nucleotide polymorphism (SNP) at Fas gene promoter in cervical carcinogenesis. METHODS: SNP at -670 of Fas gene promoter (A/G) together with human papillomavirus (HPV) types were examined in a total of 279 cervical smear samples and 8 human cervical squamous carcinoma cell lines using polymerase chain reaction and restriction fragment length...
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