Article

The cryptic gonadotropin-releasing hormone neuronal system of human basal ganglia

2021-03-06

Abstract excerpt

Human reproduction is controlled by ∼2,000 hypothalamic gonadotropin-releasing hormone (GnRH) neurons. Here we report the discovery and characterization of additional 150-200,000 GnRH-synthesizing cells in the human basal ganglia and basal forebrain. Extrahypothalamic GnRH neurons were cholinergic. Though undetectable in adult rodents, the GnRH-GFP transgene was expressed transiently by caudate-putamen cholinergic...

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Literature Corpus work: 1386cc12-6004-5632-bdd4-86cad72df37d
DOI: 10.1101/2021.03.04.433872

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