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Derivation of Diverse Hormone-Releasing Pituitary Cells from Human Pluripotent Stem Cells

1 Jun 2016

Abstract excerpt

Human pluripotent stem cells (hPSCs) provide an unlimited cell source for regenerative medicine. Hormone-producing cells are particularly suitable for cell therapy, and hypopituitarism, a defect in pituitary gland function, represents a promising therapeutic target. Previous studies have derived pituitary lineages from mouse and human ESCs using 3D organoid cultures that mimic the complex events underlying...

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PMID: 27304916
DOI: 10.1016/j.stemcr.2016.05.005

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