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Article

Human GnRH deficiency: a unique disease model to unravel the ontogeny of GnRH neurons.

Neuroendocrinology - 1 Jan 2010

Balasubramanian Ravikumar, Dwyer Andrew, Seminara Stephanie B, Pitteloud Nelly, Kaiser Ursula B, Crowley William F

Abstract excerpt

Evolutionary survival of a species is largely a function of its reproductive fitness. In mammals, a sparsely populated and widely dispersed network of hypothalamic neurons, the gonadotropin-releasing hormone (GnRH) neurons, serve as the pilot light of reproduction via coordinated secretion of GnRH. Since it first description, human GnRH deficiency has been recognized both clinically and genetically as a...

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Source

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Identifiers

PMID: 20606386
DOI: 10.1159/000314193
PMCID: PMC3214927

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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