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Kisspeptin and the Hypothalamic Control of Reproduction: Lessons from the Human

27 Sept 2012

Abstract excerpt

The hypothalamic hormone GnRH is a central driver of pituitary gonadotropin secretion, controlling pulsatile gonadotropin secretion, modulating gonadal steroid feedback, and bringing about full fertility in the adult. Thus, understanding GnRH neuronal regulation is essential to understanding the neurohumoral control of human reproduction. Genetic tools were used in patients with GnRH deficiency (i.e. idiopathic...

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PMID: 23015291
DOI: 10.1210/en.2012-1429

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