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Article

Phenotyping Angiotensin-Converting Enzyme in Blood: A Necessary Approach for Precision Medicine.

The journal of applied laboratory medicine - 1 Sept 2021

Samokhodskaya Larisa M, Jain Mark S, Kurilova Olga V, Bobkov Alexander P, Kamalov Armais A, Dudek Steven M, Danilov Sergei M

Abstract excerpt

BACKGROUND: Angiotensin-converting enzyme (ACE) metabolizes a number of important peptides participating in blood pressure regulation and vascular remodeling. Elevated ACE expression in tissues (which is generally reflected by ACE in blood) is associated with increased risk of cardiovascular diseases. Elevated ACE in blood is also a marker for granulomatous diseases. METHODS: We applied our novel approach-ACE...

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Identifiers

PMID: 34097042
DOI: 10.1093/jalm/jfab032
PMCID: PMC10949476

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