Article
Focus on increased serum angiotensin-converting enzyme level: From granulomatous diseases to genetic mutations.
Clinical biochemistry - 1 Sept 2018
Lopez-Sublet Marilucy, Caratti di Lanzacco Lorenzo, Danser A H Jan, Lambert Michel, Elourimi Ghassan, Persu Alexandre
Abstract excerpt
Angiotensin I-converting enzyme (ACE) is a well-known zinc-metallopeptidase that converts angiotensin I to the potent vasoconstrictor angiotensin II and degrades bradykinin, a powerful vasodilator, and as such plays a key role in the regulation of vascular tone and cardiac function. Increased circulating ACE (cACE) activity has been reported in multiple diseases, including but not limited to granulomatous...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
